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Efficient cosmetic lightening method against skin blemishes caused by melanin.


Cosmelan reduces and eliminates acquired skin blemishes of melanic origin, increasing skin luminosity and equalising skin tone. The Cosmelan pack provides an effective combination of professional treatment and home maintenance cream.

Action Mechanism

Cosmelan aims to reduce and eliminate skin blemishes of melanic origin

Application of Cosmelan inhibits the melanogenesis process paralysing melanin production for a long period of time during which corneum stratum flaking plus the action of the macrophagic cells taking the melanin deposits with them.

Reversible inhibition of tyrosinase activity

Inhibition of the tyrosinase is only activated during treatment application. When finished, the enzyme recovers its activity producing new melanin, particularly if there is solar stimulus. Due to this, application of topical depigmentants must be reiterative to obtain results.

Inhibitor action without damaging melanocyte

Under no circumstance does tyrosinase inhibition make the melanocytes disappear, but simply paralyses or stops melanin production, without risk of white blemishes appearing. Cosmelan action causes complementary inhibition of other enzymes involved in the eumelanin production process, like dopa tautomerase, among others.


Cosmelan 1 mask and Cosmelan 2 maintenance treatment formulas act on the different melanogenesis stages to increase effects and achieve certain synergy. they have been developed from vegetable and chemical origin to guarantee maximum level of tyrosinase inhibition.

  • Tyrosinase inhibitor complex:

Master combination of 6 functional laboratory formulated ingredients to guarantee high efficiency and skin tolerance.
Reversible action
  • Dopatautomerase and eumelanin channel inhibitor complex:

Comprises of effecient ingredients acting as enzymatic inhibitors.
  • Complementary melanogenesis inhibitor system:

Prevents melanosomes transfer to keratinocytes eliminating UV ray stimulus of melanocytes.
  • Vitamin complex:

High antioxidant, free antiradical power, stimulates collagen production and cell renewal, revitalising skin. Skin becomes more luminous and radiant.
  • Vegetable extract complex:

Vegetable origin substances with lightening properties which hydrate and soothe the skin.
  • Sunblock filters:

Combination of physical and chemical filters, with free antiradical effect neutralising UVA and UVB rays.
  • Exfoliating agent:

Accelerates natural flaking process of corneum stratum and therefore melanin elimination.
  • Preservative and perfume free cosmetic base:

Emulsion formulated to aid ingredient penetration of the epidermis.


  • Rapid lightening action:

Intervening in the advanced stage of melanogenesis.

  • For all kinds of skin blemishes of melanic origin:

Particularly efficient in reducing localised epidermis blemishes.

  • Any season of the year:

even in summer, followed by use of total sunblock to guarantee treatment effectiveness (complete moisturising sunblock or dermatological complete sunblock by Mesoestetic)

  • Good tolerance, all skin phototypes:

All Cosmelan formulas have been rigorously prepared to guarantee maximum tolerance. Apt for all phototypes and cases.

  • Proven efficiency:

Numerous “in vivo” and “in vitro” tests performed.

  • Lightening and luminosity:

It contains embeilshing agents which equalise skin tone giving it luminosity.

Cosmelan treatment:
Before getting to the cosmelan mask application stage, there's a 2 week skin prep that includes:
1 Digital Skin Analysis;
1 Hydration Facial;
1 Prep-Peel.
The prep treatments are included on the Cosmelan price.

Cosmelan Treatment   £1150
Cosmelan maintenance products: (Mandatory and not included) Cosmelan 2  
  Melan Recovery  
  moisturising sun protection SPF50+  
  anti-stress face mask  
  hydra milk cleanser  


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